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Description

Hongge L, Kexin G, Xiaojie M, Nian X, Jinsha H

median 35 months), as the first-line choice of cytotoxic therapy

The essential feature of apoptosis is the release of cytochrome c from mitochondrial, regulated by the balance of between pro-apoptotic and antiapoptotic proteins in BCL-2 family, activation of initiator caspases (caspase 8, 9, and 10) and effector caspases (caspase 3, 6 and 7) [75]

In addition, the viral vector vaccine TG4010, significantly improves progress-free survival in patients with advanced NSCLC when used in combination with chemotherapy[102]