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DOI: 10.1016/j.jpba.2024.116374

In particular, these cells are known to rely on the function of a ThDP-dependent OGDHC and malate-aspartate shuttle (Zhou et al., 2015

This allows for a more stable and sustained anabolic signal, leading to more profound effects like hyperplasia (new cell creation)

However, anatomical components that facilitate pain perception are well-formed at 25 weeks' gestation, although the ability to mount descending analgesic responses develops later during infancy