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CCI injury in adult rats produced a 250 percent increase in OH production, which was sustained for 90 minutes (Marklund et al., 2001

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To address these gaps, future research should prioritize larger scale multicenter randomized controlled trials with standardized protocols, adequately powered biomarker-guided RCTs with harmonised clinical endpoints plus GSH/GSSG, MDA/TBARS, SOD/CAT/GPx panels, head-to-head monotherapy vs