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The absence of alteration of the intestinal mucosa, which indicates the absence of toxicity and preservation of physiology and gastrointestinal integrity, was also verified by visual inspection

Consistent with this possibility, we found that continuing dilution of M22 to 1M, while clearly demonstrating intact synapses and pre-synaptic vesicles, also led to areas of tissue disruption suggestive of excessive osmotic swelling

Although the modes of action for both GH43_8 and AA5 are currently unknown their enrichment in the AGAu group may provide a function-targeted biomarker for Candida infections 135,136

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