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Some patients notice improvements within a few weeks, while others may require a few months to experience significant benefits

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(2) Synaptic Dysfunction and Neural Circuit Imbalance Dysfunction in synaptic proteins and adhesion molecules leads to disrupted excitatory/inhibitory (E/I) balance in cortical and subcortical networks

Drug design, development and therapy 8:20692074 Gurel A, Armutcu F, Sahin S, Sogut S, Ozyurt H, Gulec M, Kutlu NO, Akyol O (2004) Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys