glutathione in er lumen Intracellular pools are heterogeneously concentrated IRE1α determines ferroptosis sensitivity through
IRE1 determines ferroptosis sensitivity through regulation of glutathione synthesis Nature Communications The antioxidant glutathione plays a key role in protein folding The team discovered a few years ago that if glutathione levels aren't precisely maintained in mitochondria, all systems fail. On the heels ER stress, protein misfolding, and oxidative stress are intimately Download Scientific Diagram Pathways for thiol oxidation in the ER.Black arrows represent the entry Download Scientific Diagram
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