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Some of these problems include neurological disorders, brain atrophy, demyelination, delayed cognitive development and growth, mental retardation, lack of emotional and communicative responses, lack of smiling and willingness to play, extreme fatigue, vomiting, tremors and convulsions, gait and motor coordination disorders, severe megaloblastic anemia, thrombocytopenia, pancytopenia, which can lead to coma, respiratory failure, and death

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A key 6-year follow-up study (N=266, elderly patients aged 60-89) published in Bulletin of Experimental Biology and Medicine demonstrated that Epithalamin treatment normalized melatonin production, improved T-cell immunity markers (CD3+, CD4+, CD4/CD8 ratio), and reduced cardiovascular mortality by 28% compared to the control group