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Establishment of an orthotopic bladder cancer model in C57BL/6 mice All mice received care following the guidelines of the Care and Use of Laboratory Animals and their use followed the terms of the Institutional Animal Care regulations and Use Committee of Nanjing University

Among the various pathways EVs utilize for BBB crossing, fusion-mediated transport is particularly advantageous as it circumvents lysosomal processing, which often degrades cargo before it reaches the cytoplasm [81]

In reality, while taking Mino-xidil, it normally takes 2-4 months of consistent usage to observe a decrease in hair loss and the development of new hair

A phase II trial of TAS-102 in patients with colorectal cancer with ctDNA-defined minimal residual disease post-adjuvant therapy compared to synthetic control cohort