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These include: Large disc extrusions or sequestered fragments requiring surgical intervention Severe spinal stenosis with significant canal narrowing Bone spurs (osteophytes) compressing nerve structures Advanced degenerative disc disease with complete disc height loss Spondylolisthesis (vertebral slippage) beyond grade 1 Cauda equina syndrome (medical emergency requiring immediate surgery) Users with these conditions typically report minimal improvement from peptide therapy alone

Pepcore peptides are supplied strictly for laboratory research use only and are not for human or veterinary use

CPT code 0551U became effective April 1, 2025, and CPT code 0568U became effective October 1, 2025