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Description

NLRP3 is a protein characterized by a nucleotide-binding oligomerization domain (NOD), a leucine-rich repeat (LRR), and a pyrin domain

Warning The FDA does not approve glutathione injections for any purpose

Slight deviations in the closed-state fit likely originate from an ensemble of conformations or flexibility in regions such as UBA2UBA3, which exhibit lower confidence scores in the AlphaFold model and may allow for an expandable channel