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Transforming growth factor-beta (TGF-) is a pleiotropic cytokine that regulates various cellular processes, including cell proliferation, differentiation, apoptosis, and extracellular matrix remodeling [20]

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Corticosteroids, methotrexate, biologics like infliximab and adalimumab, they all work by dampening immune activity across the board

This stage of Lyme disease is so advanced that Lyme Literate Medical Doctors (LLMDs) often recommend intravenous antibiotics, administered through a peripherally inserted central catheter (PICC line)