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However, no significant changes were observed in fibrosis scores, although there was a trend toward more patients in the combination and vitamin E groups having improved fibrosis stages than in the placebo group

In RUO content, those signals should be handled as editorial boundaries

Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis