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68 69 Stress management

Mechanistically, glutathione is understood to inhibit the enzyme tyrosinase and shift melanin production from darker eumelanin toward lighter pheomelanin, which can make skin look brighter and more even over time

Compare to healthy cells, cancer cells are characterized by increased formation of ROS and therefore to avoid ROS-induced cell death, cancer cells restore their ROS homeostasis by increasing their antioxidant capacity (Valko et al

Furthermore, presented approach is also applicable to pre-habilitation programmes considering needs of other patient cohorts affected by chronic diseases such as CVD and orthopaedic disorders with planned major surgical incisions, who require individually adapted pre- and rehabilitation programmes