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Gut 1999, 44 (supplement 1), A36 abstract no

Doi: McKinley S, Andrew T, Morita M, Willoughby D

As a high-affinity agonist of nicotinic acetylcholine receptors (nAChRs), nicotine directly activates VTA dopamine neurons through 2 subunit-containing receptors, inducing Na + /Ca 2+ influx that causes membrane depolarization