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Molecular targets of cannabidiol in neurological disorders

Determination of serum alkaline phosphatase (ALP) activity Serum ALP activity was assessed by a colorimetric method published by Bowers and McComb [31]

The iPSC-derived cardiomyocytes and MCF-7 cells were then incubated with 6 M JC-1 dye in medium at 37 C for 30 min and HCM with TMRM dye and processed according to the manufacturers instructions (JC-1 Kit, ThermoFisher Scientific, TMRM Kit, Abcam)

145 Existing preclinical and clinical experiment data show that Gln inhibitor CB-839 joint capecitabine can effectively treat type PI3KCA mutations in colorectal cancer (NCT02861300)