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HIF-1 up-regulates the expression of Glutaminase (GLS) to promote the decomposition of glutamine into glutamate, which is further converted to -ketoglutarate (-KG), which enters the tricarboxylic acid cycle (TCA cycle) to support energy production (67)

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median age 65 years), and 3,717 AH hospitalizations (59% male

From our currently approved estimate of 2,184 respondents, we estimate that the six new MVPs finalized in this rule will result in approximately 542 individual respondents moving from traditional MIPS to MVPs (see Table 94, row (d))