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Linkage of Arsenic Methylation and Toxicity Because methylated arsenicals containing pentavalent As (MAs V and DMAs V ) were less acutely cytotoxic than iAs III , it was initially assumed that biological methylation was a process that detoxified As as a prelude to its excretion (Yamauchi and Fowler, 1994)

Webmedcentral (2013) 4:209

The difference between them in injury target and pathological process stems from the essential difference of organ metabolic function