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Experimental protocol Using a previous procedure and regimens (10-12), BPC 157 was given perorally, in drinking water (10 g/kg, 10 ng/kg, i.e., 0.16 g/mL, 0.16 ng/mL, 12 mL/rat/day) till sacrifice, or alternatively, 10 g/kg, 10 ng/kg intraperitoneally, first application at 30 min after surgery, last at 24 hours before sacrifice

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The latter possibly points to one of the compensatory mechanisms that limits long-term efficacy of bupropion and other weight loss modalities

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