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By targeting miR-223-3p/ITPR3/GPX4/xCT, the researchers successfully prevented high glucose-induced ferroptosis [123] (Table 2)

302,303,304 PINK1 accumulates on the outer membrane of damaged mitochondria and activates parkin, which then ubiquitinates several mitochondrial outer membrane proteins to initiate the autophagic pathway, engulfing damaged mitochondria to maintain mitochondrial health and function

He was the first recipient of the National Academy of Sciences Award in Chemical Sciences, in 1979

A more recent pilot study enrolling ten glioma patients utilizing the CAPP-seq-based NGS technique reported a detection rate of up to 93.8% plasma samples with successful tracking of change in mutation profiles (116)