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Description

The 4-fluoro-1-methyl-indazole group occupies the region between TM1 and TM2, making van der Waals contacts with residues in both helices

Low serum vitamin B12 concentrations in people using metformin are associated with hyperhomocysteinemia [48], a higher incidence of neuropathy [49,50], and worse neuropathy scores [51]

Serotonin and Appetite Serotonin deficiency can increase appetite and cravings for carbohydrates, contributing to weight gain

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