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Description

In recent years, polyphenolic compounds derived from pomegranate have been investigated as dietary supplements aimed at alleviating exercise-induced fatigue (52), with studies highlighting the anti-inflammatory properties of pomegranate extracts

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IL-18 is especially abundant on macrophages but also on dendritic cells, monocytes and kidney epithelial cells

it enables cells to cope with various forms of stress (e.g., nutrient deprivation, endoplasmic reticulum (ER) stress, pathogen infection, and hypoxia) and is considered a survival mechanism 5