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Further investigation showed that CPs first reduce the level of skin oxidation, inhibit the expression of the key transcription factor AP-1 (c-Jun and c-Fos), then activate the TGF-/Smad signaling pathway to promote collagen synthesis, inhibit the expression of MMP-1/3 to inhibit collagen degradation, and inhibit skin inflammation to alleviate skin aging in mice

The breakdown of tagged AFB1 with O 3 produced 3-ketones, organic acids, and volatile chemicals or mineral products such CO 2 , O 2 , and H 2 O

Notably, several proline residues of EPOP, including P320, P322, and P323 from L1, and P335 from H, jointly contribute to the critical shape complementarity of the binding interface (Fig

2026 Apr 23;22(9):4784-4805