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We also performed an open-label pilot clinical trial with GLP-1 analogs in patients with FRDA to assess whether the frataxin-inducing effect could be safely obtained in vivo

Moreover, PLK1 acts as a tumor promoter in a variety of cancers [17] and modulates autophagy [18]

doi: 10.3389/fphys.2025.1555118 Received 03 January 2025 Accepted 07 March 2025 Published 26 March 2025 Volume 16 - 2025 Edited by Cristina Espinosa-Diez, Wayne State University, United States Reviewed by Tiago J