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In another study, an antibody-modified docetaxel (DTX)-loaded targeted NLC was prepared with DSPEPEG-NH2 as a linker and revealed effective tumor site/vessel accumulation, and appropriate biodistribution [208]

Analyses of biochemical parameters, including the levels of liver enzymes in the serum (ALT, AST), indicated significant damage to the livers of mice receiving D-galactose, with D-galactose inducing oxidative stress through an increase in lipid peroxidation (MDA) and decreases in the glutathione contents in brain and liver tissues