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Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis

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The binding mode for 1j permits the formation of strong hydrophobic interactions within the apolar pocket surrounding the quinolinium N1-atom, consisting of Tyr20, Tyr204, Tyr242, Leu164, Ala198, and Ala247 residues (hydrophobic residues highlighted by red hashed lines,FIG

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