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5C) in the hippocampal CA1 region in vivo, it induced neuronal hyperactivation (Fig.5, I and M), which was undiscernible from that caused by the A oligomers alone (Fig

Ce-DAB2 staining and preparation of Drosophila larval CNS for EM The dissected flies central brain and VNC were rinsed (five times for 3 min each) with 0.15 M sodium cacodylate buffer pH 7.4 containing 2 mM CaCl 2 on ice and blocked with 20 mM glycine, 50 mM potassium cyanide and 50 mM aminotriazole in 0.15 M sodium cacodylate buffer pH 7.4 containing 2 mM CaCl 2 for 20 min on ice

Arch Pediatrie

vomitoria root aqueous extract caused up to 86% mortality at 300 mg/kg, whereas A