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doi: 10.1167/iovs.14-16126 10 DaiY.HuX.SunX

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(3A, according to which glucose-derived -ketoglutarate leaves the astrocytic TCA cycle in exchange with malate, generated via oxaloacetate (OAA), which in turn had been formed from aspartate in a transamination process

In addition, the expression of HDAC4 is also significantly upregulated, accompanied by a series of pathological damages including tubular lumen dilation, the diminished tubular epithelial cell abundance, and inflammatory cell infiltration in ioversol-induced AKI mice model and HK-2 cells exposed to ioversol