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Furthermore, it has been discovered that patients with migraine have higher blood levels of inflammatory markers linked to vascular diseases, such as homocysteine (Oterino et al., 2010), suggesting that a neuroinflammatory cascade is activated during the migraine pathogenesis (Table 2)

In one randomized placebo-controlled trial, metformin lowered B12 levels (J Intern Med 2003

Alternate day fasting : This involves fasting every other day and eating without much restriction on non-fasting days

As the reoxygenation process may increase oxidative stress, it is often considered the reason for H/R-induced ferroptosis