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Among them, At bHLH29 (FIT1, clade IIIa) and clade Ib bHLH factors ( At bHLH38, At bHLH39, At bHLH100, At bHLH101) were reported to regulate two crucial Fe responsive genes, AtIRT1 and AtFRO2 while these TFs were, in turn, regulated by yet other bHLH TFs (Colangelo and Guerinot, 2004

Resting-state functional connectivity analyses in 162 AD/MCI patients, 181 schizophrenia patients, and 315 controls showed shared and disorder-specific network abnormalities, driven mainly by default mode, visual, and subcortical networks (161)

Biomarkers may be related to the disposition and metabolism of the drug (such as APAP protein adducts) or to the endogenous response of the host to the drug