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Characterization, anti-oxidative and anti-inflammatory effects of Costa Rican noni juice ( Morinda citrifolia L.)

Physical findings : tachycardia fine tremor slurred speech stupor with palor pink eye (conjunctival injection) ataxia, incoordination, impaired driving orthostatic hypotension Medicinal uses (not FDA approved): decrease intra-occular pressure in glaucoma patients antinausea effects in patients undergoing cancer chemotherapy appetite stimulant in patients suffering from anorexia related toAIDs wasting syndrome Treatment for Overdose: supportive care (frequent reassurance and maintenance of a nonthreatening environment, minimal stimuli, judicious use of benzodiazepines when significant anxiety is present) Notes: Marijuana remains the most commonly used illicit drug in the United States The 1998 National Household Survey on Drug Abuse (NHSDA) reported that more than 72 million Americans (33%) aged 12 years and older have tried marijuana at least once in their lifetimes It is a Federal DEA category I drug (but ~14 States have made it legally available for specific medical indications, e.g

[9] Mutations in the SLITRK1, [9] [29] 5HT2A, [30] SAPAP3, [31] FOXP1, [32] and NF1 [33] genes have been associated with trichotillomania

3e), which further supports their roles as ligands for the calcium that bridges AIM and IgM