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The GSH-mediated regulation of ferroptosis has shown some promising results in the treatment of ischemic injury to the liver, kidney, brain, and heart as well as some neurodegenerative diseases [18]

Therefore, ferritin autophagy-induced ferroptosis is one of the critical mechanisms of sepsis-induced cardiac injury [71]

Glutathione is an antioxidant that naturally occurs in the body and is produced in the cells

However, using recognizable spectrophotometric features that are indicative of the catalytic sequence, most particularly three charge transfer absorption transitions, permits assignment of the order of specific common catalytic events that in turn has indicated function for four of the five variants studied