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Therefore, while metabolism-targeted combination therapies are being advanced, a systematic evaluation of their risk-benefit ratios is necessary to overcome the aforementioned limitations through rational design

338 Ferroptosis in autoimmune diseases Autoimmune diseases, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and myasthenia gravis (MG), are caused by disorders in autoimmune tolerance and the bodys immune response to the self-antigen