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Mass spectrometry analysis confirms the correct molecular weight and amino acid sequence

While both classes aim to reduce gastric acid secretion, their mechanisms, potency, and clinical applications differ significantly: PPIs (e.g., omeprazole, esomeprazole, pantoprazole) act by irreversibly inhibiting the proton pump, offering stronger and longer acid suppression ideal for GERD, peptic ulcers, and ZollingerEllison syndrome

However, some health plans have a sixth tier where they offer certain medications at a reduced cost

Probenecid markedly reduces renal clearance of ketorolac, doubling systemic exposure and prolonging half-life