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Finally, citric acid is an organic tricarboxylic acid used habitually in cosmetics for its antimicrobial and anti-oxidant effect, which contributes to the stability, effectiveness and improved appearance of the final result, as well as adding its anti-oxidant action to that of the other active principles

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This pattern suggests that oral bioavailability may vary significantly between individuals and that systemic effects require adequate absorption that not everyone achieves

By choosing the biomass of each section in the duration from 20 th May to the middle of October and the mean value of BDOC variations to analyze the relationship between the biomass and variation according to the built model, the result is shown in Fig