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Glutathione operates through several mechanisms to protect skin cells

Briefly, the recognition of SECIS by the translational machinery results in the recruitment of specific translational factors that decode in-frame UGA codons by inserting selenocysteine into elongating selenoproteins (4)

It should be noted that the absolute values should be considered in relation to the cellular concentration of the GST, such that the approximately 3- to 4-fold lower specific activities of SscGST A2-2, CjaGST A3-3, and HsaGST A1-1, if required, could be compensated for by a higher expression level of the protein

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