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Dose-response relationships: Biological effects show threshold (minimum effective concentration), linear response zone (increasing dose produces proportional benefits), and saturation (maximum benefit reached, further increases provide minimal additional effect)

This response was characterized by increased production of CD3+, CD4+, and CD8 + T cells, as well as co-stimulatory CD80 and integrins [79, 154]

Hypothetically, this drop in demyelination might circumvent the loss of fatty acid degradation by astrocytes as a trigger for neurodegeneration [60]

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