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Thus, by activating the coagulationinflammation axis, worsening the local microenvironment, promoting urate crystal aggregation, and accelerating tissue fibrosis, hypercoagulability contributes significantly to tophus development and persistence

This misinterpretation of data is possible when specific controls are not used to selectively inhibit ferroptosis as ferrostatin-1 or liproxtatin-1 [36, 37]