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Anyway, at higher concentrations, like those deriving from a high-fat diet, primary and secondary BAs can reduce gut barrier integrity with their detergent properties, causing increased intestinal permeability and, thus, oxidative stress, DNA damage, and production of inflammatory cytokines, such as IL-6 and TNF-alpha, which promote inflammation and cause the inactivation of the FXR, thereby powering a pro-inflammatory state in the colon [25]

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Abstract: In the last two decades, many new peptides have been developed, and new knowledge on how peptides improve the skin has been uncovered

Consequently, glutathione can protect our cells from damage caused by free radicals, peroxides, and heavy metals, and can improve metabolic energy