c terminus synuclein lipid binding

c terminus synuclein lipid binding Schematic representation of relevant landmarks on the protein An N-terminal alpha-synuclein fragment binds

Name: c terminus synuclein lipid binding Schematic representation of relevant landmarks on the protein An N-terminal alpha-synuclein fragment binds
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An N terminal alpha synuclein fragment binds lipid vesicles to modulate lipid induced aggregation: Cell Reports Physical Science The Synaptic Function of Synuclein Jacqueline Burr, 2015 Functional and Pathological Effects of Synuclein on Synaptic SNARE Complexes ScienceDirect Targeting synuclein aggregation with immunotherapy: a promising therapeutic approach for Parkinson's disease

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Description

Specifically, ferrous iron (Fe 2 ) reacts with hydrogen peroxide (HO) to generate highly reactive hydroxyl radicals [34], which initiate non-enzymatic lipid autoxidation and accelerate the propagation of lipid peroxides

Accessed 8/5/2015

10.3390/pharmaceutics15020625 243

These data establish KEAP1NRF2 signaling as a negative regulator of anti-tumor CD8 T cell function and identify PTGIR as a critical factor downstream of NRF2 that mediates this process