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Everything else is speculation layered on top of incomplete data

In addition, the discovery of the first specific LDHB inhibitor was recently reported 61

A key focus should be the interaction between the HIF-1-regulated iron metabolism axis (such as transferrin receptor 1 and ferritin light chain) and ferroptosis-related molecules including GPX4 and Nrf2, to establish a dynamic model connecting hypoxiaischemia, iron dysregulation, and oligodendrocyte ferroptosis, and to identify stage-specific vulnerability across oligodendrocyte maturation