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In complex chronic illnesses like Long COVID and ME/CFS, joint and muscle pain is driven by profound systemic dysfunction rather than simple wear-and-tear

As de novo synthesis of ceramide is located in the ER, which is absent in erythrocytes, it is thus assumed that erythrocytic ceramide should directly originate from the hydrolysis of sphingomyelin

Given the limitations and complexity of stroke treatment, particularly drug delivery across the BBB, there is increasing interest in vectors that cross the BBB

Individuals who naturally have gene variants of ANGPTL3 that lead to reduced levels of the protein also have reduced levels of lipids, or fats, in their blood and correspondingly, a reduced risk of heart disease