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However, these are rarely needed for standard injection site reactions

The newly freed L-carnitine is recycled back outside the membrane, ready to capture another fatty acid and keep the cellular engines running smoothly

12,13,14,15,16,17 Unfortunately, for much of the subsequent 20th century, these concepts became superseded by the neurone doctrine, such that glial responses to CNS disorders were considered to be non-specific, stereotypic, always subsequent to primary neuronal damage and of little functional consequence