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7.2 Metabolic reprogramming First-line antidiabetic agents targeting AMPK and PPAR- exhibit potent immunomodulatory and cytoprotective effects through metabolic pathway modulation

Although the authors found no major changes in gut microbiota composition or fecal metabolites at the end of the intervention, they observed significant improvements in the probiotics group compared to the placebo on two measures of non-motor symptoms of PD, the Movement Disorder Society Unified Parkinsons Disease Rating Scale (MD UPDRS I) and the Non-Motor Symptoms Scale (NMSS)

Regulation of PD-L1: a novel role of pro-survival signalling in cancer

Timepoints selected as PBMC cultures were only viable within the same media for 7 days, and so this provided the maximal amount of time to measure our variables