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Activated NLRP3 binds to an adapter proteinASC, which contains a caspase-recruitment domainfacilitating the aggregation of ASC into stable filamentous structures

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Biomed Res Int 2015:540731 Yang W, Yang Y, Yang J-Y et al (2016) Treatment with bone marrow mesenchymal stem cells combined with plumbagin alleviates spinal cord injury by affecting oxidative stress, inflammation, apoptotis and the activation of the Nrf2 pathway

The scientists suggested that there may have been a correlated increase in the animals body weight and BMC, as measured by dual X-ray absorptiometry (DXA)