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subtilis suggests that BshB2 might function as BSH- S -conjugate amidase Bca in detoxification of RES similar to the MSH- S -conjugate amidase Mca (Parsonage et al., 2010)

Reduced rates of carbohydrate digestion and absorption likely accounted for these effects

Landscapes Health & Medical Sciences (AREA) Life Sciences & Earth Sciences (AREA) General Health & Medical Sciences (AREA) Chemical & Material Sciences (AREA) Medicinal Chemistry (AREA) Pharmacology & Pharmacy (AREA) Animal Behavior & Ethology (AREA) Public Health (AREA) Veterinary Medicine (AREA) Epidemiology (AREA) Bioinformatics & Cheminformatics (AREA) Engineering & Computer Science (AREA) Diabetes (AREA) Endocrinology (AREA) Gastroenterology & Hepatology (AREA) Immunology (AREA) Proteomics, Peptides & Aminoacids (AREA) Zoology (AREA) Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA) Hematology (AREA) Obesity (AREA) Chemical Kinetics & Catalysis (AREA) General Chemical & Material Sciences (AREA) Organic Chemistry (AREA) Biophysics (AREA) Molecular Biology (AREA) Emergency Medicine (AREA) Child & Adolescent Psychology (AREA) Medicinal Preparation (AREA) Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA) Peptides Or Proteins (AREA) Abstract The present invention relates to a solid oral pharmaceutical composition comprising (i) a core comprising a GLP-1 receptor agonist, and (ii) a first coating, wherein the first coating comprises a copolymer (A) in combination with a copolymer (B) and/or a copolymer (C) and/or a copolymer (D)