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Additionally, F exposure may interact with estrogen receptor-alpha (ESR) gene polymorphisms to affect androgen-binding protein and SHBG levels in male Chinese farmers (n = 348, urinary F levels impact on serum SHBG levels [ = 0.060, 95% CI 0.101 to 0.018]) [106]

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doi: 10.1042/BSR20191242 43 SuXYinXLiuYYanXZhangSWangXet al

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Without the oversight of a formal drug approval process, users are essentially participating in an uncontrolled human experiment, which is far removed from the safety of established pharmaceutical protocols

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