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Webb, Rapid multi-echo measurement of brain metabolite T2 values at 7T using a single-shot spectroscopic Carr-Purcell-Meiboom-Gill sequence and prior information, NMR Biomed

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Conjugation reactions usually involve metabolite activation by a highenergy intermediate and have been classified into two general types: type I (e.g., glucuronidation and sulfonation), in which an activated conjugating agent combines with substrate to yield the conjugated product, and type II (e.g., amino acid conjugation), in which the substrate is activated and then combined with an amino acid to yield a conjugated product (Hodgson, 2004)

The degree of PP2A methylation is subject to changes according to metabolism