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It is possible that the observed actions occurred through a complex signaling mechanism that involves the PI3K (Phosphoinositide 3-kinases) and AMPK (AMP-activated protein kinase) pathways

Statements Author contributions BH wrote the manuscript

The product was further subjected to purification using column chromatography on silica gel in DCM: MeOH (20:1) as the mobile phase to obtain a pure sample

Binding of BRD4 ET to ASXLs is conserved ASXL1 and homologous ASXL2 and ASXL3 were identified as mutually exclusive components of the PR-DUB complex 1,29 , and all contain similar but not identical ET-binding sequences (IRIQL in ASXL1, LKIPV in ASXL2 and LKIQL in ASXL3) (Supplementary Fig