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Since PPAR- agonistic drugs such as IRB are responsible for strong organ-protective effects, including anti-fibrotic, anti-oxidant, and anti-inflammatory effects, IRB was proven to be effective in protection from CP-induced ovarian injury (Wang et al

The gpoA transcripts, as well as tpxD and ahpD , which encode the TpxD thiol peroxidase and the AhpD alkylhydroperoxidase, respectively, were upregulated when pneumococci were exposed to H 2 O 2

Renal lipid accumulation is often observed in lysosomal storage diseases such as human Fabry disease 21

If the body has insufficient antioxidants to neutralize the free radicals, the free radicals cause oxidative stress that can injure or destroy cells