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Protection against Parkinson's Disease Parkinson's disease (PD) is the second most common neurodegenerative disorder that is characterized by the progressive loss of dopaminergic cells in the substantia nigra pars compacta region of the brain, which results in motor problems including resting tremor, rigidity, bradykinesia, and postural instability [37]

These pathologic changes caused by Hcy are manifested by impaired flow-mediated vasodilation, mainly due to decreased nitric oxide (NO) production and bioavailability [80]

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The cytotoxic activity of low polarity fractions of butanol extracts from SB fruit, leaves and twigs were tested against HT29, HCT116, PC3, AGS, MCF7, HS27, and PBMCs cell lines